Eastern Equine Encephalitis (EEE) Antibodies

These mouse IgG2b monoclonal antibodies were raised against purified eastern equine encephalitis (EEE) and recognize EEE virus.

Highlights:

  • Reacts with EEE virus, epitope E1
  • Clone 1A4B-6 reacts with all alphaviruses
  • Suitable for ELISA, Indirect Immunofluorescene, Immunofluorescence and hemagglutination inhibition (HI) assay applications

Eastern equine encephalitis (EEE), commonly called Triple E or sleeping sickness is a disease caused by a zoonotic mosquito vectored Togavirus that is present in North, Central, and South America, and the Caribbean. EEE was first recognized in Massachusetts, United States, in 1831, when 75 horses died mysteriously of viral encephalitis. Symptoms include high fever, muscle pain, altered mental status, headache, meningeal irritation, photophobia, and seizures, which occur 3-10 days after the bite of an infected mosquito. EEE is closely related to Venezuelan equine encephalitis virus (VEEV) and western equine encephalitis virus (WEEV).

From a laboratory at Centers for Disease Control and Prevention.

Catalog Number Product DataSheet Size AVAILABILITY Price Qty
ECD023-FP
Anti-Eastern Equine Encephalitis [1A4B-6] Antibody, 100ug
100ug In stock
Regular Price:$345.00
On Sale:
ECD022-FP
Anti-Eastern Equine Encephalitis [1B1C-4] Antibody, 100ug
100ug 4-6 weeks
Regular Price:$345.00
On Sale:

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Specifications

Product Type: Antibody
Antigen: EEEV complex
Accession ID: P08768
Isotype: IgG2b
Clonality: Monoclonal
Clone Name: 1B1C-4
1A4B-6
Reactivity: Eastern Equine Encephalitis Virus (EEEV)
Immunogen: Clone 1B1C-4: EEE BeAn5122
Clone 1A4B-7: EEE NJ59
Species Immunized: Mouse
Epitope: E1
Purification Method: Protein G
Buffer: PBS, 0.05% (w/v) Sodium Azide
Storage: -20C
Shipped: Cold Packs

Provider
References
  1. Roehrig JT, Hunt AR, Chang GJ, Sheik B, Bolin RA, Tsai TF, Trent DW. Identification of monoclonal antibodies capable of differentiating antigenic varieties of eastern equine encephalitis viruses. Am J Trop Med Hyg. 1990 Apr;42(4):394-8. PubMed PMID: 2158755.
  2. Pässler S, Pfeffer M. Detection of antibodies to alphaviruses and discrimination between antibodies to eastern and western equine encephalitis viruses in rabbit sera using a recombinant antigen and virus-specific monoclonal antibodies. J Vet Med B Infect Dis Vet Public Health. 2003 Aug;50(6):265-9. PubMed PMID: 14628996.

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