Influenza A H3N2, A/Victoria/361/2012, Neuraminidase Antibodies
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These mouse monoclonal antibodies (IgG2b) were raised against the NA of seasonal influenza A H3N2 virus A/Victoria/361/2012.
Highlights:
- Cross reactive with the NA of all H3N2 viruses tested
- Bind to NA (N2 subtype) epitopes containing residue 346.
- Suitable for ELISA, immunofluorescence assay and NA inhibition assay
- Can be used in NA potency assessment of influenza vaccines
Influenza A H3N2 virus has long been circulating in humans together with H1N1 and influenza B viruses, resulting in annual influenza epidemics. While hemagglutinin (HA) on the surface of influenza virus is responsible for viral binding to and entry into host cells, Neuraminidase (NA) as the second most abundant surface glycoprotein facilitates the release of the progeny virions for infecting more cells. NA is also the major target of FDA-approved antivirals that are used in treating influenza.
From the laboratory of Hongquan Wan, DVM, PhD, Food and Drug Administration.
These mouse monoclonal antibodies (IgG2b) were raised against the NA of seasonal influenza A H3N2 virus A/Victoria/361/2012.
Highlights:
- Cross reactive with the NA of all H3N2 viruses tested
- Bind to NA (N2 subtype) epitopes containing residue 346.
- Suitable for ELISA, immunofluorescence assay and NA inhibition assay
- Can be used in NA potency assessment of influenza vaccines
Influenza A H3N2 virus has long been circulating in humans together with H1N1 and influenza B viruses, resulting in annual influenza epidemics. While hemagglutinin (HA) on the surface of influenza virus is responsible for viral binding to and entry into host cells, Neuraminidase (NA) as the second most abundant surface glycoprotein facilitates the release of the progeny virions for infecting more cells. NA is also the major target of FDA-approved antivirals that are used in treating influenza.
From the laboratory of Hongquan Wan, DVM, PhD, Food and Drug Administration.
| Catalog Number | Product | DataSheet | Size | AVAILABILITY | Price | Qty |
|---|
| Product Type: | Antibody |
| Accession ID: | P0DOF9 |
| Clonality: | Monoclonal |
| Clone Name: | AE11 or BH4 |
| Reactivity: | React with the NA of all H3N2 viruses tested |
| Immunogen: | Influenza A H3N2 A/Victoria/361/2012 |
| Epitope: | A highly conserved epitope containing residue 346 of NA (N2 subtype) |
| Purification Method: | Protein G |
| Buffer: | PBS, 0.05% (w/v) Sodium Azide |
| Storage: | -20C |
| Shipped: | Cold Packs |
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