Jin Wang, PhD, Baylor College of Medicine

Jin Wang, PhD
Jin Wang, PhD

The Wang laboratory is interested in developing tools for biological and biomedical studies. Currently, their research is mainly focused in three areas: 1) developing novel fluorescent probes to quantitatively monitor real-time glutathione dynamics in living cells; 2) developing small molecule inhibitor against coactivators to treat breast cancer; and 3) developing novel materials and strategies for non-viral gene delivery.

Products

References

  1. Xiqian Jiang, Chengwei Zhang, Jianwei Chen, Sungwoo Choi, Ying Zhou, Mingkun Zhao, Xianzhou Song, Xi Chen, Mirjana Maletic-Savatic, Timothy Palzkill, David Moore, Meng C. Wang, and Jin Wang*, "Quantitative Real-Time Imaging of Glutathione with Subcellular Resolution", Antioxidants & Redox Signaling. http: //DOI.org/10.1089/ars.2018.7605
  2. Jiang X, Chen J, BajiÄ? A, Zhang C, Song X, Carroll SL, Cai ZL, Tang M, Xue M, Cheng N, Schaaf CP, Li F, MacKenzie KR, Ferreon ACM, Xia F, Wang MC, MaletiÄ?-SavatiÄ? M, Wang J. Quantitative real-time imaging of glutathione. Nat Commun. 2017 Jul 13;8:16087.
  3. Jianwei Chen, Xiqian Jiang, Chengwei Zhang, Kevin R. MacKenzie, Fabio Stossi, Timothy Palzkill, Meng C. Wang, and Jin Wang*, "Reversible Reaction-Based Fluorescent Probe for Real-Time Imaging of Glutathione Dynamics in Mitochondria", ACS Sensors, 2017, ASAP. DOI: 10.1021/acssensors.7b00425
  4. Jiang X, Chen J, Wang MC, Wang J. Glutathione Quantification in Live Cells with Real-Time Imaging and Flow Cytometry. STAR Protoc. 2020 Nov 14;1(3):100170.