His research interests center on the immunobiology and molecular pathogenesis of parasitic protozoal diseases of zoonotic importance. Current research is focused on development of recombinant and synthetic vaccines for cryptosporidiosis; immunotherapy and new drug discovery for cryptosporidiosis; definition of the molecular pathogenesis of host cell recognition, attachment, and invasion by Cryptosporidium; structural characterization of Cryptosporidium glycoprotein ligands; animal model development; and improved methods for diagnosis and detection.